Gastroenterology
Current evidence of effects of Helicobacter pylori eradication on prevention of gastric cancer
Il Ju Choi
Korean J Intern Med. 2013;28(5):525-537. Published online August 14, 2013
Gastric cancer is the second most common cause of cancer death worldwide and is usually detected at a late stage, except in Korea and Japan where early screening is in effect. Results from animal and epidemiological studies suggest that Helicobacter pylori infection, and subseque..
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Current status of chemotherapy for the treatment of advanced biliary tract cancer
Takashi Sasaki, Hiroyuki Isayama, Yousuke Nakai, Kazuhiko Koike
Korean J Intern Med. 2013;28(5):515-524. Published online August 14, 2013
Chemotherapy is indispensable for the treatment of advanced biliary tract cancer. Recently, reports regarding first-line chemotherapy have increased, and first-line chemotherapy treatment has become gradually more sophisticated. Gemcitabine and cisplatin combination therapy (or gemcitabine and ox..
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Positron emission tomography detection of synchronous colon cancer in a patient with chronic lymphocytic leukemia
Jeong Eun Lee, Sang Mook Bae, Moon Sung Kim, Woo Hyeon Kim, Kyung Jin Yun, Min jung Cho, Seok-Goo Cho
Korean J Intern Med. 2013;28(4):500-503. Published online July 1, 2013
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A case of membranoproliferative glomerulonephritis associated with metastatic colon cancer
Jung-Hwa Ryu, Soon Sup Chung, Dong-Ryeol Ryu, Seung-Jung Kim, Duk-Hee Kang, Sun Hee Sung, Kyu-Bok Choi
Korean J Intern Med. 2013;28(2):254-257. Published online February 27, 2013
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Hemato-oncology
Molecular targeted therapy for advanced gastric cancer
Jong Gwang Kim
Korean J Intern Med. 2013;28(2):149-155. Published online February 27, 2013
Although medical treatment has been shown to improve quality of life and prolong survival, no significant progress has been made in the treatment of advanced gastric cancer (AGC) within the last two decades. Thus, the optimum standard first-line chemotherapy regimen for AGC remains debatable, and..
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A case of papillary fibroelastoma in the left ventricle
Joo Yong Hyun, In Hyun Jung, Hyun Jong Lee, Sook Jin Lee, Jin Seok Kim, Chan Young Na, Young Moo Ro
Korean J Intern Med. 2013;28(1):89-93. Published online December 28, 2012
Cardiac papillary fibroelastoma (CPF) is a rare and benign primary cardiac neoplasm of unknown prevalence. The incidence of CPF in the left ventricle is lower than that in other parts of the heart. A 65-year-old female was referred to our cardiology department for evaluation of a cardiac mass of..
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DNA Methylation of RUNX3 in Papillary Thyroid Cancer
Hee Ja Ko, Bo Yeon Kim, Chan Hee Jung, Sung Wan Chun, Ji Oh Mok, Yeo Joo Kim, Hyeong Kyu Park, Chul Hee Kim, Sang Jin Kim, Dong Won Byun, Kyo Il Suh, Myung Hi Yoo, Sung Gu Kang
Korean J Intern Med. 2012;27(4):407-410. Published online November 27, 2012
Background/AimsThe relationship between Runt-related transcription factor 3 (RUNX3) gene inactivation and various solid tumors has been reported; however, little information is available about RUNX3 in thyroid cancers. Met..
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Concurrent Parathyroid Carcinoma and Hyperplasia in Hyperparathyroidism
Min Young Oh, Sang Bo Oh, Hyeog Gyu Seoung, Ji Hye Kim, Sang Soo Kim, Bo Hyun Kim, In Ju Kim
Korean J Intern Med. 2012;27(3):356-359. Published online September 1, 2012
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Simultaneous Xanthogranulomatous Cholecystitis and Gallbladder Cancer in a Patient with a Large Abdominal Aortic Aneurysm
Yahya Al-Abed, Mohammed Elsherif, John Firth, Rudi Borgstein, Fiona Myint
Korean J Intern Med. 2012;27(3):338-341. Published online September 1, 2012
There have been reports of the coexistence of abdominal aortic aneurysm (AAA) with intra-abdominal malignancy including gastric, colonic, pancreatic, and renal. We herein report a case of a previously undiagnosed AAA and a presenting complaint consistent with acute cholecystitis. Following cholec..
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Role of Photodynamic Therapy in the Palliation of Obstructing Esophageal Cancer
Hyeon Young Yoon, Young Koog Cheon, Hye Jin Choi, Chan Sup Shim
Korean J Intern Med. 2012;27(3):278-284. Published online September 1, 2012
Background/AimsThe aim of this non-randomized study was to determine the role of photodynamic therapy (PDT) in a multimodal approach for the palliation of advanced esophageal carcinoma. MethodsTwenty consecutive patients with obstructing esophag..
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Parathyroid Carcinoma Presenting as a Hyperparathyroid Crisis
Alice Hyun-Kyung Tan, Hee Kyung Kim, Mi Yeon Kim, Young Lyun Oh, Jee Soo Kim, Jae Hoon Chung, Sun Wook Kim
Korean J Intern Med. 2012;27(2):229-231. Published online May 31, 2012
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A Case of Therapy-Related Acute Myeloid Leukemia Following 5-Fluorouracil Chemotherapy
Hye Jeong Park, Jung-Hye Choi, Kyeong A Lee, Hyun Cheol Kim, Young-Soo Nam, Young-Ha Oh, Woong-Soo Lee
Korean J Intern Med. 2012;27(1):115-117. Published online February 28, 2012
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Gender Differences in Susceptibility to Smoking among Patients with Lung Cancer
Jeong-Seon Ryu, Sang-Hoon Jeon, Jung-Soo Kim, Jung Hwan Lee, Seong Hyun Kim, Ji Taek Hong, Ju Hong Jeong, Ji Joong Jeong, Myung Dong Lee, Sang Joon Min, Hae-Seong Nam, Jae-Hwa Cho, Seung-Min Kwak, Hong Lyeol Lee, Hyun-Jung Kim
Korean J Intern Med. 2011;26(4):427-431. Published online November 28, 2011
Background/AimsTo determine whether female smokers are more or less susceptible to the detrimental pulmonary-function effects of smoking when compared to male smokers among patients with lung cancer. MethodsPack-years and pulmonary function indi..
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Nuclear factor E2-related factor 2 Dependent Overexpression of Sulfiredoxin and Peroxiredoxin III in Human Lung Cancer
Young Sun Kim, Hye Lim Lee, Ki Bum Lee, Joo Hun Park, Wou Young Chung, Keu Sung Lee, Seung Soo Sheen, Kwang Joo Park, Sung Chul Hwang
Korean J Intern Med. 2011;26(3):304-313. Published online September 13, 2011
Background/AimsOxidative stress results in protein oxidation and is implicated in carcinogenesis. Sulfiredoxin (Srx) is responsible for the enzymatic reversal of inactivated peroxiredoxin (Prx). Nuclear factor E2-related factor 2 (Nrf2) binds to antioxidant responsive elements..
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Primary Small Cell Carcinoma of the Lung Presenting with Breast and Skin Metastases
Fatih Altintoprak, Halil Fırat Baytekin, Canatan Tasdemir
Korean J Intern Med. 2011;26(2):207-209. Published online June 1, 2011
Cutaneous metastases originating from an internal cancer are relatively uncommon in clinical practice, and metastatic lesions to the breast are rarer than those to the skin. Skin metastases of lung cancer, which may be the first sign of the disease, usually indicate progressive disease and a poor..
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Endoscopic Cryotherapy of Lung and Bronchial Tumors: A Systematic Review
Seon-Heui Lee, Won-Jung Choi, Sook-Whan Sung, Young-Kyoon Kim, Chi-Hong Kim, Jae-Il Zo, Kwang-Joo Park
Korean J Intern Med. 2011;26(2):137-144. Published online June 1, 2011
Background/AimsWe made a systematic review and evaluation of endoscopic cryotherapy of endobronchial tumors, investigating safety and efficacy. MethodsQualified studies regarding endoscopic cryotherapy of lung tumors were systemically evaluated ..
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Efficacy and Safety of Hepatic Arterial Infusion of Fluorouracil with Leucovorin as Salvage Treatment for Refractory Liver Metastases from Colorectal Cancer
Hyun Jung Lee, Yoon Soo Lee, Keun-Wook Lee, So Yeon Kim, Chang Jin Yoon, Dong-Yeop Shin, Yun Gyoo Lee, Se Yeon Choi, Sung-Gwon Kang, Sung-Bum Kang, Jee Hyun Kim
Korean J Intern Med. 2011;26(1):82-88. Published online March 2, 2011
Background/AimsLimited options remain for patients with metastatic colorectal cancer (CRC) after failure of standard systemic chemotherapy. Readministration of chemotherapeutic agents by hepatic arterial infusion (HAI) has the rationale of providing higher concentrations of ch..
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Anaplastic Thyroid Carcinoma Initially Presented with Abdominal Cutaneous Mass and Hyperthyroidism
Kyu-Hyoung Lim, Keun-Wook Lee, Jee Hyun Kim, So Yeon Park, Sung-Hee Choi, Jong Seok Lee
Korean J Intern Med. 2010;25(4):450-453. Published online November 27, 2010
A 63-year-old female was admitted to our hospital with a tender abdominal wall mass about 15 cm in diameter, which she had for 1 month. About 1 week earlier, the patient had also perceived a mass in the neck area. Computed tomography revealed huge thyroid and periumbilical masses. The thyroid hor..
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Clinical Significance of Observation without Repeated Radioiodine Therapy in Differentiated Thyroid Carcinoma Patients with Positive Surveillance Whole-Body Scans and Negative Thyroglobulin
Dong-Jun Lim, Joo Hyun O, Min-Hee Kim, Ji-Hyun Kim, Hyuk-Sang Kwon, Sung-Hoon Kim, Moo-Il Kang, Bong-Yun Cha, Kwang-Woo Lee, Ho-Young Son
Korean J Intern Med. 2010;25(4):408-414. Published online November 27, 2010
Background/AimsCurrently, there is no consensus on the necessity of repeated radioiodine therapy (RAI) in patients who show iodine uptake in the thyroid bed on a diagnostic whole-body scan (DxWBS) despite undetectable thyroglobulin (Tg) levels after remnant ablation. The prese..
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The Role of Photodynamic Therapy for Hilar Cholangiocarcinoma
Young Koog Cheon
Korean J Intern Med. 2010;25(4):345-352. Published online November 27, 2010
The prognosis for hilar cholangiocarcinoma is limited by tumor spread along the biliary tree leading to refractory obstructive cholestasis, cholangitis, and liver failure. Palliation with biliary endoprostheses results in median survival times of 4-6 months for advanced bile duct cancer. Photodyn..
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